to stop having a close relationship with someone, especially stop living with them, or to change a course of action that you have had for a long time

You've been in your job for years - it's time you made a break. 那份工作你已干了多年了——是时候改变一下了。

make a clean break When a relationship ends, it's often best to make a clean break (= suddenly and completely stop seeing each other).

She promised that her presidency would make a break with the past.

For anyone looking to make a break from city life, this must be the perfect place.

See also: break noun (END)